E-MTAB-3469 - Differential gene expression between BGC-823/NC and BGC-823/MTA2, SGC-7901/NC and SGC-7901/shMTA2 cells

Status
Submitted on 9 December 2013, released on 8 April 2015, last updated on 8 July 2016
Organism
Homo sapiens
Samples (4)
Array (1)
Protocols (5)
Description
Metastasis associated 1 family, member 2 (MTA2) gene is classified to metastasis associated gene family. We have previously reported that MTA2 gene was overexpressed in gastric cancer tissues, correlating with tumor invasion, lymph node metastasis, and advanced TNM stage. MTA2 knockdown significantly inhibited gastric cancer cell invasion and metastasis. Yet, its molecular mechanisms are still unclear. The aim of this study is to investigate the molecular mechanisms of MTA2 in regulating malignant behaviors of gastric cancer. This experiment captures the expression data between BGC-823/NC and BGC-823/MTA2, SGC-7901/NC and SGC-7901/shMTA2 cells using Whole human genome microarray 4×44K (Design ID: 014850, Agilent technologies).
Experiment types
transcription profiling by array, case control design
Contact
Citations
MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11. Zhou C , Ji J , Cai Q , Shi M , Chen X , Yu Y , Zhu Z , Zhang J. BMC Cancer 15:343 (2015), PMID:25929737
MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11. Zhou C, Ji J, Cai Q, Shi M, Chen X, Yu Y, Zhu Z, Zhang J. :343 (2015), PMID:25929737
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-3469.idf.txt
Sample and data relationshipE-MTAB-3469.sdrf.txt
Processed data (1)E-MTAB-3469.processed.1.zip
Array designA-AGIL-28.adf.txt