E-MTAB-3224 - Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines

Status
Submitted on 30 September 2014, last updated on 5 January 2016, released on 5 January 2016
Organism
Homo sapiens
Samples (12)
Array (1)
Protocols (4)
Description
SN-38 resistant breast cancer cell lies (MCF-7 and MDA-MB-231) were established by stepwise increasing the concentration of SN-38. Gene expression profiling was performed on parental (sensitive) MCF-7 and parental (sensitive) MDA-MB-231 cell lines and their respective SN-38 resistant cell lines. For each cell line we harvested RNA from three independent passages and conducted 3 arrays.
Experiment types
transcription profiling by array, case control design, compound treatment design
Contact
Citation
Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines. Jandu H, Aluzaite K, Fogh L, Thrane SW, Noer JB, Proszek J, Do KN, Hansen SN, Damsgaard B, Nielsen SL, Stougaard M, Knudsen BR, Moreira J, Hamerlik P, Gajjar M, Smid M, Martens J, Foekens J, Pommier Y, Brünner N, Schrohl AS, Stenvang J. :34 (2016), PMID:26801902
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-3224.idf.txt
Sample and data relationshipE-MTAB-3224.sdrf.txt
Raw data (1)E-MTAB-3224.raw.1.zip
Array designA-GEOD-13497.adf.txt