E-MTAB-3153 - Microarray analysis of DNA methylation in metastatic versus non metastatic breast cancers
Submitted on 29 July 2010, released on 20 March 2015, last updated on 8 July 2016
19 non-metastatic breast cancers (controls) and 19 breast cancers showing metastases or metastatic relapse within 5 years (cases) were extracted from a multi-institutional case series of 123 breast cancer patients . Cases and controls were analyzed for DNA methylation over 56 genes by the MethDet assay using a dedicated microarray (MethDet56). 1. Levenson VV, Melnikov AA: The MethDet: a technology for biomarker development. Expert Rev Mol Diagn 2011, 11:807-812.
methylation profiling by array, case control design
A seven-gene CpG-island methylation panel predicts breast cancer progression. Yan Li, Anatoliy A. Melnikov, Victor Levenson, Emanuela Guerra, Pasquale Simeone, Saverio Alberti and Youping Deng. BMC Cancer 15:417 (2015), PMID:25986046
A seven-gene CpG-island methylation panel predicts breast cancer progression. Li Y, Melnikov AA, Levenson V, Guerra E, Simeone P, Alberti S, Deng Y. :417 (2015), PMID:25986046