E-MTAB-3133 - Transcription profiling by array of compare two pairs of Burkholderia cenocepacia ST32 clinical isolates (from cystic fibrosis patients) subjected to cultivation in two different conditions
Last updated on 28 November 2014, released on 27 February 2015
Burkholderia cenocepacia sequence type 32 (ST32) represents one of the most globally distributed strains from Bukrholderia cepacia complex (Bcc), which infected 30% of Czech cystic fibrosis (CF) patients. The aim of this study was to compare gene expression in two pairs of ST32 clinical isolates that were subjected to cultivation in two different conditions, characteristic for chronic B. cenocepacia infection in CF patients. ST32 strain is known to be a problematic epidemic strain, which caused a serious outbreak at the Prague CF centre.
transcription profiling by array, development or differentiation design, growth condition design, pathogenicity design, reference design, replicate design, strain or line design
Gene expression profiling of Burkholderia cenocepacia at the time of cepacia syndrome: loss of motility as a marker of poor prognosis?. Kalferstova L, Kolar M, Fila L, Vavrova J, Drevinek P. :1515-1522 (2015), PMID:25694518