E-MTAB-3117 - Exendin-4 treatment of Pancreatic Islets
Released on 13 November 2014, last updated on 19 November 2014
The aim of the study was to investigate the effect of Exendin-4 on isolated pancreatic islets allowing for the elucidation of the various transcriptional programs initiated by this multifunctional peptide hormone. Islets were treated with Exendin-4 for 30 and 180 minutes. After these time points, RNA was isolated and used for hybridization against matched control islets using the Mouse PancChip 6.
transcription profiling by array, compound treatment design, time series design