E-MTAB-2479 - MicroRNA profiling of tumor and stromal tissue in metastatic colorectal paitents
Last updated on 3 November 2014, released on 4 November 2014
Specific MicroRNAs (miRNAs) have been found up- or down-regulated in colorectal cancer, and they are associated with prognosis or response to chemotherapy or targeted drugs. The microenvironment close to the neoplasm plays a leading role in tumor spread and survival. We used microarray technology to profile miRNA expression both in primary tumor and stromal tissue to study differences and clinical implications.
transcription profiling by array, cell type comparison design, co-expression, replicate design
Analysis of differential miRNA expression in primary tumor and stroma of colorectal cancer patients. Della Vittoria Scarpati G, Calura E, Di Marino M, Romualdi C, Beltrame L, Malapelle U, Troncone G, De Stefano A, Pepe S, De Placido S, D'Incalci M, Marchini S, Carlomagno C. Biomed Res Int (2014), PMID: 25143946