E-MTAB-2248 - SNP array analysis of seven tumor cell lines carrying MYC amplifications
Last updated on 23 January 2014, released on 13 May 2014
In order to clarify the mechanism to MYC (8q24) amplification as dmin or hsr, we finely investigated the organization of amplicons in seven tumor cell lines [four SCLC, one AML, and two Colon Carcinoma (CC)] by integrating next-generation sequencing (NGS), Fluorescent in situ hybridization (FISH), PCR, and array-based approaches.
genotyping by array, comparative genomic hybridization by array, disease state design, genotype design, in vitro
Genomic organization and evolution of double minutes/homogeneously staining regions (dmin/hsr) with MYC amplification in human cancer. LÍAbbate Alberto, Macchia Gemma, DÍAddabbo Pietro, Lonoce Angelo, Tolomeo Doron, Trombetta Domenico, Kok Klaas, Bartenhagen Christoph, Whelan Christopher W, Palumbo Orazio, Severgnini Marco, Cifola Ingrid, Dugas Martin, Carella Massimo, De Bellis Gianluca, Rocchi Mariano, Carbone Lucia, Storlazzi Clelia Tiziana.
Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer. LAbbate A, Macchia G, DAddabbo P, Lonoce A, Tolomeo D, Trombetta D, Kok K, Bartenhagen C, Whelan CW, Palumbo O, Severgnini M, Cifola I, Dugas M, Carella M, De Bellis G, Rocchi M, Carbone L, Storlazzi CT. :9131-9145 (2014), Europe PMC 25034695