E-MTAB-2164 - Transcription profiling by array of mouse pre-B cells treated with Ara-C, Pam3CSK4, or a combination of both to test whether the compounds synergize in rendering tumor cells more immunogenic
Released on 1 March 2014, last updated on 3 June 2014
The low immunogenicity of many cancer cells and the immunosuppression by various cancers and anti-cancer therapies have been an obstacle in the development of efficacious immunotherapies. Our goal was to test if TLR agonists and anti-cancer chemotherapeutic agents synergize in rendering tumor cells more immunogenic.
transcription profiling by array, co-expression, compound treatment design, in vitro