E-MTAB-2126 - microRNA profiling by array of human breast cancer cell lines exposed to Cediranib
Released on 5 May 2014, last updated on 3 June 2014
We investigated the effect of Cediranib in human mammary carcinoma cell lines Hs578T, MDA-MB-231 and T47D by cellular and molecular assays. The cellular assays determined the ability to inhibit cell growth (IC50) by MTS assay, cell migration and invasion. Furthermore, using a microRNA-array and qRT-PCR approach we assessed the comparative expression of microRNAs following Cediranib treatment
microRNA profiling by array, co-expression, compound treatment design, in vitro
MicroRNA profiling of human breast cancer cell lines exposed to the Cediranib. Rodrigues AL, Evangelista AF, Macedo T, Oliveira RJS, Reis RM, Marques MM.