E-MTAB-2086 - Transcription profiling by array of human primary fibroblasts as they progress into senescence

Status
Last updated on 16 June 2014, released on 17 June 2014
Organism
Homo sapiens
Samples (12)
Array (1)
Protocols (5)
Description
Transcription profiling from human primary fibroblasts as they progress into senescence. Samples were taken early population doubling onwards until cells reached replicative senescence and stopped dividing. Population doubling values are contained in Characteristics[generation] column.
Experiment types
transcription profiling by array, co-expression, development or differentiation design, replicate design
Contact
Citations
A genomics approach identifies senescence-specific gene expression regulation. Lackner, D. H., Hayashi, M. T., Cesare, A. J. and Karlseder, J. Aging Cell  (2014)
Reorganization of chromosome architecture in replicative cellular senescence. Criscione SW, De Cecco M, Siranosian B, Zhang Y, Kreiling JA, Sedivy JM, Neretti N. :e1500882 (2016), Europe PMC 26989773
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-2086.idf.txt
Sample and data relationshipE-MTAB-2086.sdrf.txt
Raw data (1)E-MTAB-2086.raw.1.zip
Array designA-AFFY-141.adf.txt
Links