E-MTAB-2086 - Transcription profiling by array of human primary fibroblasts as they progress into senescence
Last updated on 16 June 2014, released on 17 June 2014
Transcription profiling from human primary fibroblasts as they progress into senescence. Samples were taken early population doubling onwards until cells reached replicative senescence and stopped dividing. Population doubling values are contained in Characteristics[generation] column.
transcription profiling by array, co-expression, development or differentiation design, replicate design
A genomics approach identifies senescence-specific gene expression regulation. Lackner, D. H., Hayashi, M. T., Cesare, A. J. and Karlseder, J. Aging Cell (2014)
Reorganization of chromosome architecture in replicative cellular senescence. Criscione SW, De Cecco M, Siranosian B, Zhang Y, Kreiling JA, Sedivy JM, Neretti N. :e1500882 (2016), Europe PMC 26989773