E-MTAB-2062 - Transcription profiling by array of primary human leukocyte subsets to investigate the effect of cell-type–specific regulatory hypomethylated regions identified in methylation studies

Status
Released on 31 December 2013, last updated on 2 May 2014
Organism
Homo sapiens
Samples (36)
Array (1)
Protocols (4)
Description
Genome-wide methylation patterns observed in primary human leukocyte subsets were used to identify cell-type–specific regulatory hypomethylated regions. To investigate the possible effect of these regions on gene expression, a transcriptomics analysis was performed with mRNA isolated from the leukocyte subsets.
Experiment types
transcription profiling by array, all pairs, cell type comparison, co-expression
Contact
Citations
Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type–specific hypomethylated regions. M. Zilbauer, T.F. Rayner, C. Clark, A.J. Coffey, C.J. Joyce, P. Palta, A. Palotie, P.A. Lyons, K.G.C. Smith.
Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type-specific hypomethylated regions. Zilbauer M, Rayner TF, Clark C, Coffey AJ, Joyce CJ, Palta P, Palotie A, Lyons PA, Smith KG. :e52-60 (2013), Europe PMC 24159175
Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type specific hypomethylated regions. Zilbauer M, Rayner TF, Clark C, Coffey AJ, Joyce CJ, Palta P, Palotie A, Lyons PA, Smith KG. Blood  (2013), Europe PMC 24159175
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-2062.idf.txt
Sample and data relationshipE-MTAB-2062.sdrf.txt
Raw data (1)E-MTAB-2062.raw.1.zip
Processed data (1)E-MTAB-2062.processed.1.zip
Array designA-AFFY-168.adf.txt
Links