E-MTAB-1874 - Transcription profiling by array of Anopheles gambiae isofemale families from Tororo, Uganda
Released on 3 December 2013, last updated on 3 June 2014
Anopheles gambiae isofemale families from Tororo, Uganda were assayed for resistance to lambda-cyhalothrin (1.5hr exposure). Resistant families were compared to susceptible families. A portion of each family was exposed to 0.05% lambda-cyhalothrin in order to determine the family phenotype. The families used for the array were of known phenotype but were themselves unexposed.
transcription profiling by array, co-expression, loop design, strain or line design
Parallel evolution or purifying selection, not introgression, explains similarity in the pyrethroid detoxification linked GSTE4 of Anopheles gambiae and An. arabiensis. Wilding CS, Weetman D, Rippon EJ, Steen K, Mawejje HD, Barsukov I, Donnelly MJ. :201-215 (2015), Europe PMC 25213601