E-MTAB-1796 - Transcriptional profiling of LIF stimulation in mouse embryonic stem cells
Released on 1 August 2013, last updated on 23 October 2014
Stat3+/+ and -/- ES cells were cultured in defined conditions and exposed to leukemia inhibitory factor (LIF) in a 24h timecourse to identify Stat3-independent targets of the self-renewal response to LIF signaling.
RNA-seq of coding RNA, RNA-seq of non coding RNA, co-expression, growth condition design, in vitro, stimulus or stress design
Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor. Graziano Martello, Paul Bertone, Austin Smith. EMBO Journal 32(19):2561-2574 (2013), Europe PMC 23942233