E-MTAB-1779 - Transcription profiling by RT-PCR of lymphocytes from individuals exposed to styrene and unexposed controls to identify a panel of genes involved in styrene exposure
Released on 23 September 2013, last updated on 3 June 2014
Whole blood was collected for styrene-exposed and control workers subjects in a fiberglass boat industry. Total RNA was extracted from blood lymphocytes, and cDNA was synthesized for profiling on the Human Stress and Toxicity PathwayFinder(tm) RT2 Profiler(tm) PCR Expression Array (PAHS-003, SABiosciences).
transcription profiling by RT-PCR, in vivo, stimulus or stress
Occupational Styrene Exposure Induces Stress-Responsive Genes Involved in Cytoprotective and Cytotoxic Activities. Elisabetta Strafella, Massimo Bracci, Sara Staffolani, Nicola Manzella, Daniele Giantomasi, Matteo Valentino, Monica Amati, Marco Tomasetti, Lory Santarelli. PLoS ONE 8(9):e75401 (2013)
Occupational styrene exposure induces stress-responsive genes involved in cytoprotective and cytotoxic activities. Strafella E, Bracci M, Staffolani S, Manzella N, Giantomasi D, Valentino M, Amati M, Tomasetti M, Santarelli L. :e75401 (2013), Europe PMC 24086524