E-MTAB-1722 - Transcription profiling by array of liver samples from FXR+/+ (wt) and liver-specific FXR KO (lKO) mice
Released on 1 July 2013, last updated on 11 December 2014
To identify genes regulated by FXR in mouse liver, we compared gene expression profiles in livers of FXR+/+ (wt) and liver-specific FXR KO (lKO) mice
transcription profiling by array, co-expression, genetic modification design, genotyping design, in vivo
THE HEPATIC OROSOMUCOID/ALPHA-1-ACID GLYCOPROTEIN GENE CLUSTER IS REGULATED BY THE NUCLEAR BILE ACID RECEPTOR FXR. Geoffrey Porez, Barbara Gross, Janne Prawitt, Céline Gheeraert, Bart Staels and Philippe Lefebvre.