E-MTAB-1719 - Transcription profiling by array of cells obtained from the pleura of patients with mesothelioma

Status
Released on 4 April 2014, last updated on 3 June 2014
Organism
Homo sapiens
Samples (38)
Array (1)
Protocols (6)
Description
A Cartes d’Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net/) | Affymetrix HG-U133 Plus 2.0 : 43 samples. Characteristics[OS.event] means the survival status (0: dead/1:alive). Characteristics[OS_delay] means the survival delay form diagnosis to the last follow up. Characteristics[Asbestos.Exposure] : exposure history to the asbestos (E: Exposed, PE: probably exposed, NE: not exposed). BAP1.Gene.mutation: (M: mutated, WT: wild type). Characteristics[CDKN2B.Gene.mutation]: (M: mutated, WT: wild type) . Characteristics[CTNNB1.Gene.mutation]: (M: mutated, WT: wild type). Characteristics[NF2.Gene.mutation]: (M: mutated, WT: wild type). Characteristics[P14ARF.Gene.mutation]: (M: mutated, WT: wild type). Characteristics[P16INKa.Gene.mutation]: (M: mutated, WT: wild type). Characteristics[TP53.Gene.mutation]: (M: mutated, WT: wild type). Characteristics[molecular.subgroup]: the clusters identified by the unsupervised analyses of gene expression. NOTE: This experiment was updated on 10th April 2014. The following changes were made: 5 samples (MPM39, MPM40, MPM41, MPM42, MPM430) and their associated data files were removed. Histology values were updated and the column headings regarding gene mutations were modified.
Experiment types
transcription profiling by array, co-expression, normalization testing
Contact
Citation
Molecular Classification of Malignant Pleural Mesothelioma: Identification of a Poor Prognosis Subgroup Linked to the Epithelial-to-Mesenchymal Transition. de Reyni�s A, Jaurand MC, Renier A, Couchy G, Hysi I, Elarouci N, Galateau-SallŽ F, Copin MC, Hofman P, Cazes A, Andujar P, Imbeaud S, Petel F, Pairon JC, Le Pimpec-Barthes F, Zucman-Rossi J, Jean D.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MTAB-1719.idf.txt
Sample and data relationshipE-MTAB-1719.sdrf.txt
Raw data (3)E-MTAB-1719.raw.1.zip, E-MTAB-1719.raw.2.zip, E-MTAB-1719.raw.3.zip
Processed data (1)E-MTAB-1719.processed.1.zip
Array designA-AFFY-44.adf.txt
Links