E-MTAB-1442 - Transcription profiling by array of Ubiquitin Specific Protease 2 (Usp2) knockout mice to investigate the renal transcriptome
Released on 20 March 2013, last updated on 3 May 2014
Renal transcriptome analysis of Usp2 knockout mice. Please note 'Zeitgeber time 12' means 12 hours after light onset in 12h: light 12h dark housing conditions. It is of importance in the present design because of the strong circadian oscillation of the interest gene. In the Characteristics[genetic modification] column Usp2-Lac0-SA-IRES-lacZ-WT Neo/Kan is the name of the targeting cassette which was inserted in the gene, in opposition to non for the WT who carry no mutation.
transcription profiling by array, co-expression, genetic modification, in vivo
Mice carrying Ubiquitin Specific Protease 2 (Usp2) gene inactivation maintain normal sodium balance and blood pressure. Daniel Pouly, Anne Debonneville, Dorothee Ruffieux-Daidie, Marc Maillard, Johannes Loffing and Olivier Staub.