E-MTAB-1422 - Transcription profiling by array of human precusor B cell subsets from children and adults

Status
Released on 1 July 2013, last updated on 28 October 2015
Organism
Homo sapiens
Samples (44)
Array (1)
Protocols (5)
Description
Through differentiation-stage dependent analysis and pair wise comparisons between children and adults of 5 precursor B cell subsets, we identified several mechanisms that suggest tighter checkpoint control in adult precursor B cells.
Experiment types
transcription profiling by array, all pairs, co-expression, development or differentiation
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Citations
Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin. Rother MB, Jensen K, van der Burg M, van de Bovenkamp FS, Kroek R, van IJcken WF, van der Velden VH, Cupedo T, Olstad OK, van Dongen JJ, van Zelm MC. :33924 (2016), Europe PMC 27658954
MIAME
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