E-MTAB-1324 - Transcription profiling by array of fission yeast (Schizosaccharomyces pombe) to study the effects of upf1-delta on RNA stability
Released on 3 June 2013, last updated on 5 June 2014
The Upf1 protein is a major factor in nonsense-mediated decay. We used an in vivo labelling system (Cleary et al. 2005 Nat Biotechnol. 23, 232-7) to estimate the decay rates of upf1delta and wild type cells over-expressing the transcription factor Mei4.
transcription profiling by array, cell type comparison, dye swap
Functional characterization of Upf1 targets in Schizosaccharomyces pombe. Matia-Gonzalez AM, Hasan A, Moe GH, Mata J, Rodriguez-Gabriel MA. RNA Biol 10(6):1057-1065 (2013), Europe PMC 23619768