E-MIMR-43 - Transcription profiling of ovarian gene expression in RIP140 wild type, heterozygous and knock out mice
Released on 11 May 2005, last updated on 3 May 2014
Title: Comparison of ovarian gene expression in RIP140 wild type, heterozygous and knock out mice.
Description: RIP140 null mice fail to ovulate. This experiment was designed to
determine the gene expression profile of these animals compared
to wild type and heterozygous animals following hormone treatments
that induce the biological changes required for ovulation to occur.
transcription profiling by array, compound treatment, genetic modification
Embryo transfer experiments and ovarian transplantation identify the ovary as the only site in which the nuclear receptor interacting protein1/RIP140 action is crucial for female fertility. Leonardsson, G.