E-MEXP-969 - Transcription profiling of breast cancer cells with TET-OFF regulated ERb expression treated with estradiol or ICI, an estrogen receptor antagonist
Released on 17 December 2007, last updated on 3 May 2014
Assess the full impact of estrogen receptor beta on transcription by a full transcriptome analysis of ERa and ERb-mediated gene regulation in T47D breast cancer cell line with TET-OFF regulated ERb expression.
co-expression, compound treatment, dye swap, genetic modification, loop, transcription profiling by array
Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression. Williams C, Helguero L, Edvardsson K, Haldosén LA, Gustafsson JA. :R26 (2009), Europe PMC 19426500
A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells. Williams C, Edvardsson K, Lewandowski SA, Ström A, Gustafsson JA.