E-MEXP-745 - Transcription profiling of heptatocytes from mice given a high-copper diet

Status
Submitted on 16 June 2006, released on 1 June 2007, last updated on 2 May 2014
Organism
Mus musculus
Samples (16)
Array (1)
Protocols (8)
Description
In order to study the physiological consequences of a high-copper diet on hepatic gene expression, 6 mM CuCl2 was added to the drinking water for a period of 1 month. After this period, livers of seven control mice and eight copper-treated mice were isolated and were subjected to microarray analysis and copper measurements. The hepatic gene expression profile of copper-treated mice was compared to non-treated mice using a pooled reference.
Experiment types
transcription profiling by array, compound treatment
Contacts
Erik Sluiters <e.c.sluiters@med.uu.nl>, Bart van de Sluis, Cisca Wijmenga, Frank Holstege, Harm van Bakel, Leo Klomp, Patricia Muller
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MEXP-745.idf.txt
Sample and data relationshipE-MEXP-745.sdrf.txt
Raw data (1)E-MEXP-745.raw.1.zip
Processed data (1)E-MEXP-745.processed.1.zip
Array designA-UMCU-7.adf.txt
R ExpressionSetE-MEXP-745.eSet.r