E-MEXP-745 - Transcription profiling of heptatocytes from mice given a high-copper diet
Submitted on 16 June 2006, released on 1 June 2007, last updated on 2 May 2014
In order to study the physiological consequences of a high-copper diet on hepatic gene expression, 6 mM CuCl2 was added to the drinking water for a period of 1 month. After this period, livers of seven control mice and eight copper-treated mice were isolated and were subjected to microarray analysis and copper measurements. The hepatic gene expression profile of copper-treated mice was compared to non-treated mice using a pooled reference.
transcription profiling by array, compound treatment
Erik Sluiters <firstname.lastname@example.org>, Bart van de Sluis, Cisca Wijmenga, Frank Holstege, Harm van Bakel, Leo Klomp, Patricia Muller