E-MEXP-3899 - Transcription profiling by array of C. elegans dauer stage larve with or without extreme dessication stress to study the nematode's molecular strategies in surviving extreme desiccation
Released on 23 August 2013, last updated on 23 July 2014
Many organisms in the nature can drive themselves into an ametabolic state known as anhydrobiosis upon extreme desiccation. The nematode C. elegans is one of them. However, the anhydrobiotic ability of the worm is limited to a special developmental stage known as the dauer. Besides, the dauer larvae must be first treated by a mild desiccation stress (preconditioning) so that they gain desiccation tolerance. In this study, we investigated the differential gene expression during preconditioning in the C. elegans dauer.
transcription profiling by array, co-expression, in vivo, physiological process, replicate design, stimulus or stress design
Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation. Erkut C, Vasilj A, Boland S, Habermann B, Shevchenko A, Kurzchalia TV. PLoS One 8(12):e82473 (2013), PMID:24324795