E-MEXP-3826 - Transcription profiling by array of human epithelooid sarcoma cells enriched for cancer stem-like cells (CSCs) or cancer-initiating cells (CICs) in epithelioid sarcoma against those without such enrichment
Last updated on 6 January 2014, released on 7 January 2014
Several human cancers contain a small subpopulation of cells called cancer stem-like cells (CSCs)/cancer initiating cells (CICs), which are defined by the ability of self- renewal, multi-differentiation potential, and tumorigenesis. In current study, we focused on epithelioid sarcoma, which is very rare caner, and isolated CSCs/CICs from epitheloid sarcoma cell line ESX based on ALDH activity using ALDEFLUOR assay towards identification of a new CIC/CSC marker. We performed gene profiling between ALDHhigh and ALDH low cells using cDNA microarray for the identification of good markers of CSCs/CICs of epithelioid sarcoma.
transcription profiling by array, cell type comparison, co-expression, in vitro