E-MEXP-3761 - Transcription profiling by array of human myotubues derived from three patients carrying mutations in LPIN1 gene and three matched controls with or without TNF-alpha/IL-1-beta treatment
Released on 17 October 2013, last updated on 19 October 2015
Transcriptom profiling performed on myotubes derived from 3 patients carrying two recessively-inherited mutations in LPIN1 gene and 3 age and sex matched controls with or without TNF-alpha plus IL-1-beta stimulation for 24h.
transcription profiling by array, co-expression, compound treatment, in vivo, individual genetic characteristics
Combination of lipid metabolism alterations and their sensitivity to inflammatory cytokines in human lipin-1-deficient myoblasts. Michot C, Mamoune A, Vamecq J, Viou MT, Hsieh LS, Testet E, Lainé J, Hubert L, Dessein AF, Fontaine M, Ottolenghi C, Fouillen L, Nadra K, Blanc E, Bastin J, Candon S, Pende M, Munnich A, Smahi A, Djouadi F, Carman GM, Romero N, de Keyzer Y, de Lonlay P. , Europe PMC 23928362