E-MEXP-3745 - Transcription profiling by array of murine thymus medulla in the absence and presence of acute graft-versus-host disease

Status
Released on 20 December 2012, last updated on 20 October 2015
Organism
Mus musculus
Samples (24)
Array (1)
Protocols (5)
Description
To investigate gene expression profile of medullary thymic epithelial cells with high surface density of MHC class II (mTEChigh), a murine parent into F1 hematopoietic stem cell transplantation model was administered. As recipient mice (B6xDBA/2)F1 (B6D2F1) were used that received either a syngeneic transplant from a (B6xDBA/2)F1 mouse or an allogeneic transplant from a B6 mouse, which leads to acute graft-versus-host disease (aGVHD). mTEChigh (CD45-EpCAM+Ly51-UEA1+MHCIIhigh) are sorted by FACS.
Experiment types
transcription profiling by array, co-expression, compound treatment design, disease state, in vivo
Contact
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MEXP-3745.idf.txt
Sample and data relationshipE-MEXP-3745.sdrf.txt
Raw data (1)E-MEXP-3745.raw.1.zip
Array designA-AFFY-130.adf.txt
Links