E-MEXP-3703 - Transcription profiling by array of abx1 deletion or over expression in Streptococcus agalactiae and comparision with the effect of CovS and CovR deletion
Released on 26 February 2013, last updated on 3 May 2014
Analysis of the impact of the abx1 deletion or over expression on S. agalactaie transcription profile and comparision to the effect of CovS and CovR deletion on transcriptomic profile. Some of the mutants are gene_knock_out mutants, but in other strains we have tested the over expression of the Abx1 protein by an chromosomic overexpression, or by a plasmid overexpression. Chromosomic overexpression is indicated with a K and plasmid overexpression with a V.
transcription profiling by array, co-expression, genetic modification, replicate
The Abi-domain Protein Abx1 Interacts with the CovS Histidine Kinase to Control Virulence Gene Expression in Group B Streptococcus. Arnaud Firon, Asmaa Tazi, Violette Da Cunha, Sophie Brinster, Elisabeth Sauvage,Shaynoor Dramsi, Douglas T. Golenbock, Philippe Glaser, Claire Poyart, Patrick Trieu-Cuot. PLoS Pathogens (2013)
The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus. Firon A, Tazi A, Da Cunha V, Brinster S, Sauvage E, Dramsi S, Golenbock DT, Glaser P, Poyart C, Trieu-Cuot P. :e1003179 (2013), PMID:23436996