E-MEXP-3524 - Response of a rat cornea to chemical injury
Released on 18 January 2012, last updated on 2 May 2014
Neutrophil infiltration occurres in two phases during sterile inflammation to cornea: small initial phase (Phase I) that began within 15 min, and larger second phase (Phase II) that peaked at 24-48 h. Microarrays were used to identify candidate stimuli that initiated the two phases.
transcription profiling by array, co-expression, disease state, in vivo, injury, time series
Identification of the HSPB4/TLR2/NF-kappaB axis in macrophage as a therapeutic target for sterile inflammation of the cornea.