E-MEXP-3379 - RNAi knockdown of GLI1 in human pancreatic adenocarcinoma cells
Released on 31 March 2012, last updated on 2 May 2014
Panc1 (human pancreatic adenocarcinoma cells) cells were transfected with control siRNA (targeting firefly luciferase, siLuc) or siRNA targeting GLI1 (siGLI1, Pool of four siRNAs). 72h following transfection, RNA was prepared for array analysis.
transcription profiling by array, cellular modification, co-expression, in vitro, quality control testing, replicate
GLI1 inhibitionpromotes epithelial-to-mesenchymal transition in pancreatic cancercells. Joost S, Almada LL, Rohnalter V, Holz PS, Vrabel AM, Fernandez-BarrenaMG, McWilliams RR, Krause M, Fernandez-Zapico ME, Lauth M. Cancer Res. 72(1):88-99 (2012), PMID:22086851