E-MEXP-337 - Transcription profiling by array of human T-cell differentiation
Released on 1 July 2005, last updated on 9 May 2012
To gain more insight into initiation and regulation of T cell receptor (TCR) gene rearrangement during human T cell development, we analyzed TCR gene rearrangements by quantitative PCR analysis in nine consecutive T-cell developmental stages, including CD34+ lin- cord blood cells as a reference. The same stages were used for gene expression profiling using DNA microarrays.
transcription profiling by array, development or differentiation
New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling. Dik WA, Pike-Overzet K, Weerkamp F, de Ridder D, de Haas EF, Baert MR, van der Spek P, Koster EE, Reinders MJ, van Dongen JJ, Langerak AW, Staal FJ.