E-MEXP-2539 - Transcription profiling in primary mouse hepatocytes discriminates between true and false genotoxic compounds
Released on 11 January 2011, last updated on 21 February 2012
Primary mouse hepatocytes are applied in this study as an in vitro system to discriminate false positive GTX compounds from true GTX compounds.
co-expression, compound treatment, in vitro, time series, transcription profiling by array
Assessing Concordance of Drug-Induced Transcriptional Response in Rodent Liver and Cultured Hepatocytes. Sutherland JJ, Jolly RA, Goldstein KM, Stevens JL. :e1004847 (2016), PMID:27028627
Discrimination for true and false genotoxins.