E-MEXP-209 - Transcription profiling of wounds from ovariectomized MIF null mice and controls to investigate the role of MIF during wound healing using BALB/C MIF null mice

Status
Released on 5 November 2005, last updated on 2 May 2014
Organism
Mus musculus
Samples (12)
Array (1)
Protocols (11)
Description
The aim of this experiment was to investigate the role of MIF during wound healing using BALB/C MIF null mice and in the context of reduced estrogen-associated impaired healing using ovariectomized mice (a mouse model of age-associated delayed healing). Ageing is associated with delayed cutaneous wound healing resulting from reduced estrogen levels. Macrophage migration inhibitory factor (MIF - NCBI RefSeq: NM_010798) is thought to mediate the effects of estrogen on wound healing. Gene expression was compared between wounds from ovariectomized MIF null mice and controls.
Experiment types
transcription profiling by array, genetic modification, injury
Contact
Citation
Macrophage Migration Inhibitory Factor: A Central Regulator of Wound Healing. Hardman, Matthew J.; Waite, Alexander; Zeef, Leo; Burow, Matthew; Nakayama, Toshinori; Ashcroft, Gillian S.
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-MEXP-209.idf.txt
Sample and data relationshipE-MEXP-209.sdrf.txt
Raw data (1)E-MEXP-209.raw.1.zip
Processed data (1)E-MEXP-209.processed.1.zip
Array designA-AFFY-23.adf.txt
R ExpressionSetE-MEXP-209.eSet.r
Links