E-MEXP-1141 - Transcription profiling of human A431 epidermoid carcinoma cells grown in media with antibodies against all three LN-332 chains to elucidate their molecular mechanisms of tumor growth inhibition
Submitted on 22 June 2007, released on 14 June 2008, last updated on 2 May 2014
To elucidate the molecular mechanisms of tumor growth inhibition caused by the anti-LN-332 antibodies, we plated human A431 cells on plates coated with fibroblast-derived matrix for 6 hours and then added a mixture of antibodies against all three LN-332 chains or control IgG to the medium for 16 hours. All cells from antiobody treated and controls were collected and subjected to global transcriptome analysis using Affymetrix Human Genome U133 Plus 2.0 Arrays.
transcription profiling by array, cellular process, co-expression, growth condition, in vitro