E-MEXP-1120 - Transcription profiling of Streptomyces coelicolor strain M667 as a control for thiostrepton treatment
Submitted on 22 May 2007, released on 1 August 2007, last updated on 3 June 2014
As a control for the effect of thiostrepton on gene expression in Streptomyces coelicolor, cultures of strain M667 [DrelA tipAp::] that lacks the truncated relA gene downstream of the thiostrepton-inducible promoter were treated with thiostrepton. Samples were harvested at 30 min intervals following induction for comparison to a control set of samples from aliquots of the same cultures that were not induced.
transcription profiling by array, co-expression, in vivo, stimulus or stress, time series
The global role of ppGpp in morphological differentiation and antibiotic production in Streptomyces coelicolor A3(2). Andrew Hesketh, Joan Chen, Jamie Ryding, Sherman Chang, Mervyn Bibb. Genome Biol
The global role of ppGpp synthesis in morphological differentiation and antibiotic production in Streptomyces coelicolor A3(2). Hesketh A, Chen WJ, Ryding J, Chang S, Bibb M. :R161 (2007), Europe PMC 17683547