E-MEXP-1062 - Transcription profiling of mouse embryos 1.5, 3 and 6 hr after maternal treatment with the teratogen sodium valproate
Released on 28 March 2008, last updated on 2 May 2014
The antiepileptic drug valproic acid (vpa) is known teratogen giving neural tube defects (ntd:s). Administration of vpa to female NMRI on gestation day 8 induces a high incidence of ntd. In this study we investigate the time dependent gene expression changes induced in the embryo 1.5, 3 respectively 6 hr after maternal sodium valproate treatment.
co-expression, compound treatment, in vivo, transcription profiling by array