E-MEXP-104 - Transcription profiling of mouse pressure overload induced cardiomyopathy in gp130 knock-out mice
Submitted on 23 April 2004, released on 30 June 2004, last updated on 13 May 2014
Comparison between wild-type and cardiomyocyte-restricted knock-out of IL6 cytokines receptor component gp130 after surgical intervention for pressure-overload induced cardiomyopathy.
transcription profiling by array, disease state, genetic modification
Small proline-rich protein 1A is a gp130 pathway- and stress-inducible cardioprotective protein. Pradervand S, Yasukawa H, Muller OG, Kjekshus H, Nakamura T, St Amand TR, Yajima T, Matsumura K, Duplain H, Iwatate M, Woodard S, Pedrazzini T, Ross J, Firsov D, Rossier BC, Hoshijima M, Chien KR. EMBO J 23(22):4517-4525 (2004), Europe PMC 15510217