Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-974 - Transcription profiling of human left ventricular apex samples
Submitted on 16 January 2004, released on 2 October 2007, last updated on 27 March 2012
19 paired human left ventricular apex samples were harvested at the time of implant of a left ventricular assist device (PRE) and at the time of explant (POST). The cohort included patients that were clinically classified as ischemic (I) showing evidence of coronary artery disease, non-ischemic (N) no evidence of coronary artery disease or acute Myocardial infarction (IM) myocardial infarction within 10 days of the implant. Tissue was processed and hybridized to the Affymetrix HG-U133A chip.
transcription profiling by array, disease state, individual comparison, time series
Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks. Jennifer L Hall, Suzanne Grindle, Xinqiang Han, David Fermin, Soon Park, Yingjie Chen, Robert J Bache, Ami Mariash, Zhanjun Guan, Sofia Ormaza, Jeanne Thompson, Judith Graziano, Shireen E de Sam Lazaro, Shuchong Pan, Robert D Simari, Leslie W Miller. Physiol Genomics 17(3):283-91 (2004)