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E-GEOD-974 - Transcription profiling of human left ventricular apex samples

Status
Submitted on 16 January 2004, released on 2 October 2007, last updated on 27 March 2012
Organism
Homo sapiens
Samples (37)
Array (1)
Protocols (2)
Description
19 paired human left ventricular apex samples were harvested at the time of implant of a left ventricular assist device (PRE) and at the time of explant (POST). The cohort included patients that were clinically classified as ischemic (I) showing evidence of coronary artery disease, non-ischemic (N) no evidence of coronary artery disease or acute Myocardial infarction (IM) myocardial infarction within 10 days of the implant. Tissue was processed and hybridized to the Affymetrix HG-U133A chip.
Experiment types
transcription profiling by array, disease state, individual comparison, time series
Contact
Citation
Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks. Jennifer L Hall, Suzanne Grindle, Xinqiang Han, David Fermin, Soon Park, Yingjie Chen, Robert J Bache, Ami Mariash, Zhanjun Guan, Sofia Ormaza, Jeanne Thompson, Judith Graziano, Shireen E de Sam Lazaro, Shuchong Pan, Robert D Simari, Leslie W Miller. Physiol Genomics 17(3):283-91 (2004)
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-974.idf.txt
Sample and data relationshipE-GEOD-974.sdrf.txt
Raw data (1)E-GEOD-974.raw.1.zip
Processed data (1)E-GEOD-974.processed.1.zip
Array designA-AFFY-33.adf.txt
R ExpressionSetE-GEOD-974.eSet.r
Links