E-GEOD-9649 - Transcription profiling by array of human mammary epithelial cells exposed to different environmental stresses: hypoxia, lactic acidosis, lactosis, acidosis and a combination of hypoxia and lactic acidosis
Released on 13 January 2009, last updated on 30 April 2015
Human Mammalian Epithelial Cells (HMEC) were exposed to different environmental stresses, including hypoxia, lactic acidosis, the combination of hypoxia and lactic acidosis, lactosis , as well as acidosis. We used microarrays to examine the genomic programs of cells incubated under different microenvironments. Experiment Overall Design: HMEC cells were exposed to different environmental stresses and RNAs were extracted and put on Affymetrix microarrays. We gathered RNAs from cells grown in regular media (control), lactic acidosis, hypoxia, the combinatino of lactic acidosis and hypoxia, lactosis, as well as acidosis.
transcription profiling by array, unknown experiment type
The genomic analysis of lactic acidosis and acidosis response in human cancers. Chen JL, Lucas JE, Schroeder T, Mori S, Wu J, Nevins J, Dewhirst M, West M, Chi JT.