E-GEOD-8920 - Transcription profiling of human H69 xenograft tumors in mice following PDT treatment
Submitted on 30 August 2007, released on 16 June 2008, last updated on 10 June 2011
The response of tumors to PDT treatment is expected to provide information on effects of oxygen depletion, induced apoptosis, induction of an inflammatory response and induction of an ani-tumor immune response. Experiment Overall Design: NCI-H69 human SCLC xenografts were induced in SCID mice. Three pairs of xenograft tumors, PDT treated and untreated controls, were harvested four hours after PDT treatment. RNA was isolated and prepared for hybridization to human Affymetrix GeneChip arrays.
transcription profiling by array, unknown experiment type