E-GEOD-8434 - Transcription profiling of inner ears from Errb mutant mice and wild type littermate controls
Submitted on 10 July 2007, released on 16 June 2008, last updated on 27 March 2012
Transcriptional profiles were compared in microdissected lateral walls of the inner ears from Errb mutant mice and wild type littermate controls. The goal is to identify transcriptional targets of Errb and candidate genes for inner ear diseases. Experiment Overall Design: Errb mutant mice were generated by conditional knock-out strategy. Inner ears from 10 mice were pooled for each sample and 3 replicates of wild type and mutant samples were analyzed.
transcription profiling by array, unknown experiment type
Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis. Jichao Chen, Jeremy Nathans. Dev Cell 13(3):325-37 (2007)