E-GEOD-7895 - Transcription profiling of human airway epithelial cells to investigate the reversible and permanent effects of tobacco smoke exposure

Status
Submitted on 24 May 2007, released on 16 June 2008, last updated on 27 March 2012
Organism
Homo sapiens
Samples (104)
Array (1)
Protocols (4)
Description
RNA was obtained from histologically normal bronchial epithelium of never, former, and current smokers undergoing fiberoptic bronchoscopy. Statistical analysis of the gene expression data identified gene differentially expressed between current and never smokers and classified these genes as irreversible, slowly reversible, or rapidly reversible based on their behavior in former smokers Experiment Overall Design: Microarrays run on total RNA obtained from Bronchial Epithelium of Never Smokers (n=21), Former Smokers (n=31), and Current Smokers (n=52)
Experiment types
transcription profiling by array, unknown experiment type
Contact
Citation
Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression. Jennifer Beane, Paola Sebastiani, Gang Liu, Jerome S Brody, Marc E Lenburg, Avrum Spira. Genome Biol 8(9):R201 (2007)
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-7895.idf.txt
Sample and data relationshipE-GEOD-7895.sdrf.txt
Raw data (3)E-GEOD-7895.raw.1.zip, E-GEOD-7895.raw.2.zip, E-GEOD-7895.raw.3.zip
Processed data (1)E-GEOD-7895.processed.1.zip
Array designA-AFFY-33.adf.txt
R ExpressionSetE-GEOD-7895.eSet.r
Links