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E-GEOD-75097 - Microarray gene expression profiles of peripheral blood mononuclear cells (PBMC) in patients with obstructive sleep apnea and primary snoring

Status
Released on 31 December 2015, last updated on 1 January 2016
Organism
Homo sapiens
Samples (48)
Array (1)
Protocols (5)
Description
Therefore, we extended our investigation into OSA patients with long-term continuous positive airway pressure (CPAP) treatment, hypertension, or excessive daytime sleepiness (EDS) by analyzing whole-genome gene expression profiles of PBMC in three comparisons: (1) treatment-naïve moderate to very severe OSA patients versus subjects with primary snoring; (2) moderate to very severe OSA patients with hypertension or EDS versus those without hypertension or EDS, respectively; (3) treatment-naïve very severe OSA patients versus those receiving at least one year of adequate CPAP treatment. We analyzed whole-genome gene expression profiles of peripheral blood mononuclear cells from 48 patients with sleep-disordered breathing stratified into four groups: primary snoring (PS), moderate to severe OSA (MSO), very severe OSA (VSO), and very severe OSA patients with long-term continuous positive airway pressure (CPAP) treatment (VSOC).
Experiment type
transcription profiling by array 
Contacts
yungche chen <tlm8570@gmail.com>, Kuang-Den Chen, Yung-Che Chen
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-75097.idf.txt
Sample and data relationshipE-GEOD-75097.sdrf.txt
Processed data (1)E-GEOD-75097.processed.1.zip
Additional data (1)E-GEOD-75097.additional.1.zip
Array designA-GEOD-10904.adf.txt
Links