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E-GEOD-73626 - Genome-wide DNA methylation study of hip and knee osteoarthritic and healthy cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in osteoarthritis

Released on 1 July 2016, last updated on 11 July 2016
Homo sapiens
Samples (18)
Array (1)
Protocols (5)
Cartilage samples were collected from hip or knee joint replacement patients either due to primary OA or hip fractures as controls. DNA was extracted from the collected cartilage and assayed by Illumina Infinium HumanMethylation450 ‎BeadChip array, which allows for the analysis of >480,000 CpG sites. Bisulphite converted DNA from 5 hip osteoarthritic, 6 knee osteoarthritic and 7 hip healhty cartilage samples were hybridised to the Illumina Infinium HumanMethylation450 ‎BeadChip array
Experiment type
methylation profiling by array 
Andrew Furey, Erfan Aref-Eshghi, Glynn Martin, Guang Sun, Guangju Zhai, Ming Liu, Patricia E Harper, Proton Rahman, Roger Green, Yuhua Zhang
Investigation descriptionE-GEOD-73626.idf.txt
Sample and data relationshipE-GEOD-73626.sdrf.txt
Raw data (1)
Processed data (1)
Additional data (1)
Array designA-GEOD-13534.adf.txt