Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.

E-GEOD-73626 - Genome-wide DNA methylation study of hip and knee osteoarthritic and healthy cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in osteoarthritis

Status
Released on 1 July 2016, last updated on 11 July 2016
Organism
Homo sapiens
Samples (18)
Array (1)
Protocols (5)
Description
Cartilage samples were collected from hip or knee joint replacement patients either due to primary OA or hip fractures as controls. DNA was extracted from the collected cartilage and assayed by Illumina Infinium HumanMethylation450 ‎BeadChip array, which allows for the analysis of >480,000 CpG sites. Bisulphite converted DNA from 5 hip osteoarthritic, 6 knee osteoarthritic and 7 hip healhty cartilage samples were hybridised to the Illumina Infinium HumanMethylation450 ‎BeadChip array
Experiment type
methylation profiling by array 
Contacts
Andrew Furey, Erfan Aref-Eshghi, Glynn Martin, Guang Sun, Guangju Zhai, Ming Liu, Patricia E Harper, Proton Rahman, Roger Green, Yuhua Zhang
Citation
MIAME
PlatformsProtocolsVariablesProcessedRaw
Files
Investigation descriptionE-GEOD-73626.idf.txt
Sample and data relationshipE-GEOD-73626.sdrf.txt
Raw data (1)E-GEOD-73626.raw.1.zip
Processed data (1)E-GEOD-73626.processed.1.zip
Additional data (1)E-GEOD-73626.additional.1.zip
Array designA-GEOD-13534.adf.txt
Links