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E-GEOD-72424 - A Genome-wide mRNA Screen and Functional Analysis Reveal FOXO3 as a Candidate Gene for Chicken Growth

Released on 27 August 2015, last updated on 6 September 2015
Gallus gallus
Samples (4)
Protocols (4)
The objective of this study was to identify candidate genes associated with chicken growth and investigate their potential mechanisms. We used RNA-Seq to study the breast muscle transcriptome in high and low tails of Recessive White Rock (WRRh, WRRl) and Xinghua chickens (XHh, XHl). A total of 60, 23, 153 and 359 differentially expressed genes were detected in WRRh vs. WRRl, XHh vs. XHl, WRRh vs. XHh and WRRl vs. XHl, respectively. GO, KEGG pathway and gene network analyses showed that CEBPB, FBXO32, FOXO3 and MYOD1 played key roles in growth. The functions of FBXO32 and FOXO3 were validated. Examination of mRNA profiles in two-tail samples of WRR and XH strains.
Experiment type
RNA-seq of coding RNA 
Chen Biao <>, Qinghua Nie, Xiaomei He
Exp. designProtocolsVariablesProcessedSeq. reads
Investigation descriptionE-GEOD-72424.idf.txt
Sample and data relationshipE-GEOD-72424.sdrf.txt
Processed data (1)