Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-68800 - The RNA-binding protein Musashi1 is a central regulator of adhesion pathways in glioblastoma
Released on 29 June 2015, last updated on 19 August 2015
The conserved RNA-binding protein Musashi1 (MSI1) has emerged as a key oncogenic factor in numerous solid tumors, including glioblastoma. However, its mechanism of action has not yet been established comprehensively. We set out to map its impact on the transcriptome in U251 cells using RNA-seq and iCLIP. Examination of gene expression and splicing changes upon KD of Musashi1 in U251 cells and link to iCLIP-identified Musashi1 RNA binding sites
RNA-seq of coding RNA
Philip James Uren <email@example.com>, Luiz O Penalva, Philip J Uren
The RNA-binding protein Musashi1 is a central regulator of adhesion pathways in glioblastoma. Uren PJ, Vo DT, Rosa de Araujo P, Pï¿½tschke R, Burns SC, Bahrami-Samani E, Qiao M, de Sousa Abreu R, Nakaya HI, Correa BR, Kï¿½hnï¿½l C, Ule J, Martindale JL, Abdelmohsen K, Gorospe M, Smith AD, Penalva LO.