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E-GEOD-68800 - The RNA-binding protein Musashi1 is a central regulator of adhesion pathways in glioblastoma

Status
Released on 29 June 2015, last updated on 19 August 2015
Organism
Homo sapiens
Samples (9)
Protocols (3)
Description
The conserved RNA-binding protein Musashi1 (MSI1) has emerged as a key oncogenic factor in numerous solid tumors, including glioblastoma. However, its mechanism of action has not yet been established comprehensively. We set out to map its impact on the transcriptome in U251 cells using RNA-seq and iCLIP. Examination of gene expression and splicing changes upon KD of Musashi1 in U251 cells and link to iCLIP-identified Musashi1 RNA binding sites
Experiment type
RNA-seq of coding RNA 
Contacts
Philip James Uren <uren@usc.edu>, Luiz O Penalva, Philip J Uren
Citation
The RNA-binding protein Musashi1 is a central regulator of adhesion pathways in glioblastoma. Uren PJ, Vo DT, Rosa de Araujo P, P�tschke R, Burns SC, Bahrami-Samani E, Qiao M, de Sousa Abreu R, Nakaya HI, Correa BR, K�hn�l C, Ule J, Martindale JL, Abdelmohsen K, Gorospe M, Smith AD, Penalva LO.
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-GEOD-68800.idf.txt
Sample and data relationshipE-GEOD-68800.sdrf.txt
Processed data (1)E-GEOD-68800.processed.1.zip
Links