Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-68266 - Expression data of mouse NIH3T3 and NIH3T3-k-ras transformed cell lines after Forskolin treatment
Released on 24 October 2015, last updated on 8 December 2015
Forskolin treatment induces activation of protein kinase A. This activation protects transformed cells from death induced by glucose starvation. We used microarray to identify the mechanisms involved in such a pro-survival effect. NIH3T3 and NIH3T3-K-ras were plated at 1mM glucose and then daily treated or not with 10uM FSK until 72h of growth. The microarray analysis has been performed at 72h in order to identify specific mechanisms associate with transformed cells survival.
transcription profiling by array
Ferdinando Chiaradonna, Roberta Palorini, Yuri Pirola