Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-63327 - Expression data from Regulatory T Cells either exposed to normal salt media or high salt media (+40mM NaCl)
Released on 18 November 2014, last updated on 28 November 2014
Sodium Chloride Inhibits Suppressive Function of Foxp3+ Regulatory T Cells Given the functional changes observed secondary to exposure to high-salt we wanted to know what expression based changes were taking place in the regulatory T cell population that might help to explain the evidenced functional deficits. Regulatory T Cells (Tregs) were incubated either in the presence or absence of an additional 40mM NaCl for 3 days with anti-CD3/anti-CD28 to ascertain phenotypic and expression based changes in the cellular population.
transcription profiling by array
Mitja Mitrovic <email@example.com>, Amanda L Hernandez, David A Hafler