Please note that we have stopped the regular imports of Gene Expression Omnibus (GEO) data into ArrayExpress. This may not be the latest version of this experiment.
E-GEOD-63159 - microRNA expression signatures of imatinib-treated and non-treated gastrointestinal stromal tumors
Status | Released on 1 August 2015, last updated on 19 August 2015 | ||||||||||
Organism | Homo sapiens | ||||||||||
Samples (34) | |||||||||||
Array (1) | |||||||||||
Protocols (5) | |||||||||||
Description | We performed microRNA expression profiling in a series of fresh-frozen neoadjuvantly imatinib-treated and non-treated gastrointestinal stromal tumors (GIST), using a microarray approach. Significant differentially expressed microRNAs among imatinib-treated and non-treated groups were identified using SAM analysis. Agilent microarray platform with probes matching 903 human microRNAs was used to determine miRNA expression profiles in 34 GISTs (19 imatinib-treated and 15 non-treated). Re-analysis of GSE45901 for 17 imatinib-treated GISTs. To validate the microarray platform, the expression levels of selected microRNAs were evaluated using qRT-PCR. | ||||||||||
Experiment type | transcription profiling by array | ||||||||||
Contacts | Pinar Akcakaya <pinar.akcakaya@ki.se>, Anastasia Gangaev, Catharina Larsson, Erik Berglund, Jan Åhlen, Katarina Zeljic, Mehran Ghaderi, Pinar Akçakaya, Robert Bränström, Stefano Caramuta, Weng-Onn Lui | ||||||||||
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