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E-GEOD-62856 - Functional characterization of C. elegans Y-box binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes (RIP-Seq)

Status
Released on 8 January 2015, last updated on 21 March 2015
Organism
Caenorhabditis elegans
Samples (12)
Protocols (4)
Description
We present a basic characterization of the function of Y-box binding proteins (YBPs) in C. elegans. YBPs in other organisms are known RNA-binding proteins. Our global analysis of associated mRNAs supports a role of YBPs as general mRNA binders in C.elegans. FLAG IPs were performed on transgenic animals expressing FLAG-tagged versions of either CEY-1, CEY-2, or CEY-4. MYC IPs served as controls. All IPs were performed in duplicates. 12 samples in total.
Experiment types
other, RNA-seq of coding RNA 
Contacts
Dimos Gaidatzis <d.gaidatzis@fmi.ch>, Andreas Arnold, Rafal Ciosk
Citation
Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes. Arnold A, Rahman MM, Lee MC, Muehlhaeusser S, Katic I, Gaidatzis D, Hess D, Scheckel C, Wright JE, Stetak A, Boag PR, Ciosk R. , PMID:25378320
MINSEQE
Exp. designProtocolsVariablesProcessedSeq. reads
Files
Investigation descriptionE-GEOD-62856.idf.txt
Sample and data relationshipE-GEOD-62856.sdrf.txt
Additional data (1)E-GEOD-62856.additional.1.zip
Links