E-GEOD-611 - Transcription profiling of brain and gut neurospheres of wild type and Bmi-1 knockout mice to reveal that Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
Released on 15 December 2007, last updated on 27 March 2012
The cRNA derived from Brain and Gut neurospheres of wild type and BMI-1 knockout mice were hybridized to Affymetrix mouse ver 2 Chips A, B and C. In case of brain neurospheres, the cRNA were generated by one round RNA amplification (conventional method). In contrast, the cRNA of Gut neurospheres were generated by two round RNA amplifications.
transcription profiling by array, cell type comparison, co-expression, individual genetic characteristics
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Anna V Molofsky, Ricardo Pardal, Toshihide Iwashita, In-Kyung Park, Michael F Clarke, Sean J Morrison.